Care.com logo
Log inJoin now

Find Trusted Daycares in Defiance, MO

Browse 40 trusted daycares in Defiance, MO. Compare reviews, rates, and availability to find the best fit for your child.

Start matching
Hero image

Recent daycare reviews from local parents in Defiance, MO

Daycares in Defiance, MO are rated 3.0 out of 5 stars based on 2 reviews of the 40 listed daycares

Ages & Stages Learning Center

So kind and loving! Love everything here. My kids have soared and are more than ready for kindergarten!

- Jenn K

Kiddie Academy of O'Fallon

My children attended Kiddie Academy from 12 weeks until graduating Pre-K. The whole care team was loving, passionate, and took amazing care...

- Natalie V.

Inspire - Lake St. Louis North

Always teaching and doing fun activities, parents get updates from straight from the teachers and communication with them is the easiest....

- Yaheem J.

Daycare Centers Near Defiance

IllustrationSmallDayCare image

Ages & Stages Learning Center

3925 Highway D Defiance, MO

3.0(2)
Child care
Ages & Stages Learning Center is an early childhood facility that offers early care and education programs for infants up to school-age children. The company serves families living in the Defiance, Missouri area, and its services are open to kids of up to sixteen years of age. Ages & Stages Learning Center’s programs focus on...

Jenn K says "So kind and loving! Love everything here. My kids have soared and are more than ready for kindergarten!"

See info
Academic
Day Care
Child care
Preschool
Kiddie Academy offers educational, age-specific child care programs. Our flexible, standard based curriculum is uniquely designed to help your child thrive in both school and life, while our safe and nurturing environment allows them to have fun while they learn. Learn more about what makes Kiddie Academy a leader in early...

Natalie V. says "My children attended Kiddie Academy from 12 weeks until graduating Pre-K. The whole care team was loving, passionate, and took amazing care of my girls....

See info
Inspire - Lake St. Louis North's Photo

Inspire - Lake St. Louis North

2240 LAKE SAINT LOUIS BLVD LAKE ST LOUIS, MO

5.0(3)

State license verified

Day Care
Child care
Preschool
Welcome to Tyke Town Lake St. Louis, by Kids & Company! This location is “by” Kids & Company because it retains the location and building of the previous daycare, Tyke Town, but was purchased by Kids & Company and now operates with our staff and proprietary programming. We are in a free-standing and private building...

Yaheem J. says "Always teaching and doing fun activities, parents get updates from straight from the teachers and communication with them is the easiest. All around a...

See info
Epic ChildCare's Photo

Epic ChildCare

17795 Wild Horse Creek Rd Chesterfield, MO

5.0(2)
Developmental (play-based)
Faith based
Outdoor/nature
Child care
Our school provides a fun learning environment for children ages infant to five years old. Our preschool offers an age appropriate. focused curriculum taught by our outstanding faculty. Scheduling a tour is a great 1st step. We are also the creator of Kindergarten Confidence: We prepare your child for an exciting but...

Sandi B says "We love Epic. The attention to detail is a real blessing. Gracie and Dori are so good with our kids."

See info
Inspire Lake St Louis South's Photo

Inspire Lake St Louis South

2998 TECHNOLOGY DR LAKE ST LOUIS, MO

5.0(3)

State license verified

Day Care
Child care
Preschool
ABC Daycare & Learning Center opened its doors in St Charles County, Missouri in 1990. ABC’s goal is to give every family that attends our schools a sense of pride and a satisfaction about having their children enrolled with us. We want your children to know how special they are in this world and how special they are to ABC. Our...

Yaheem J. says "Always teaching and doing fun activities, parents get updates from straight from the teachers and communication with them is the easiest. All around a...

See info
THE MORGAN SCHOOL's Photo

THE MORGAN SCHOOL

7401 S OUTER 364 DARDENNE PR, MO

5.0(10)

State license verified

starting at
$1220/mo
Developmental (play-based)
Academic
Child care
The Morgan School provides a child-centered environment, and our program focuses on the development of the whole child. The Morgan School is independently owned and operated by a licensed, degreed educator who has a passion for children and teaching; The Morgan School is not a bottom-line driven, corporately owned business...

Care Member says "My child was there for 5 years. They and I loved it."

See info
CHESTERFIELD ACADEMY CHRISTIAN SCHOOL, INC.'s Photo

CHESTERFIELD ACADEMY CHRISTIAN SCHOOL, INC.

17661 WILD HORSE CREEK RD CHESTERFIELD, MO

5.0(2)

State license verified

Child care
Preschool
At Chesterfield Academy, we create the best possible environment by creating developmentally appropriate and stimulating programs created specifically for each age. We partner with parents in cultivating those budding roots and wings. To help their roots grow and wings sprout, we go beyond just childcare to provide...

Mark S. says "Nothing but great things to say. They make you feel like you are a part of their family. We have been there for 5 years. My oldest will be leaving to...

See info
Motivation Station's Photo

Motivation Station

247 Fairway Green Drive O Fallon, MO

5.0(7)
Now enrolling for Summer 2024! Get ready to have the best summer yet! Summer hours are 7:30 am- 3:30 pm Monday- Friday on select weeks. Each week is a different theme with daily activities based on the week's theme! Message to request the informational packet and registration link for Summer 2024! During the...

Care Member says "Sarah has been watching my daughter for 2 years, and I highly recommend her! She is great with communication (regular emailed newsletters, a yearbook,...

See info
Cadence Academy Preschool 's Photo

Cadence Academy Preschool

9983 WINGHAVEN BLVD O FALLON, MO

State license verified

Child care
Day Care
With over 20 years of experience providing exceptional childcare and preschool programs for children from 6 weeks to 12 years old, Cadence Academy O’Fallon is ready to help you make the most of your child’s first educational experiences. We recently changed our name from West County Day School O’Fallon to Cadence Academy...
See info
Jana's Photo

Jana

2858 Royallvalley Way O Fallon, MO

I am a stay at home mom of three. My oldest two are in school and my daughter will be 2 in July. I also watch my friend's son who will be 2 in September. I provide breakfast, lunch, snacks, and drinks. I am available Mon-Fri, 6 am til 5:30 pm. I am located on hwy k near hwy n.
See info
Kidsplay Preschool & Childcare - O'Fallon, MO's Photo

Kidsplay Preschool & Childcare - O'Fallon, MO

2949 HIGHWAY K O FALLON, MO

State license verified

starting at
$1196/mo
Developmental (play-based)
Academic
Child care
Kidsplay was founded by a parent and teacher who wanted to create a special place for children to "just be kids" while their parents were assured of a safe, secure, quality childcare and preschool program. Kidsplay's unique design is a reflection of twenty five years of focusing on the needs of families and providing a flexible...
See info
O2B Kids Lake St. Louis's Photo

O2B Kids Lake St. Louis

1000 WYNDGATE RIDGE DR LAKE ST LOUIS, MO

State license verified

Child care
Day Care
Welcome to O2B Kids Lake St. Louis (formerly Bright Start Lake St. Louis), in St. Charles County in Missouri, serving Infants, Toddlers and PreK children! O2B Kids Lake St. Louis is conveniently located on the corner of Highway North and Wyndgate Ridge Drive, near Wyndgate Meadows, Shady Creek and Preston Woods. The first...
See info
Yogi Bear's Jellystone Park Resort's Photo

Yogi Bear's Jellystone Park Resort

5300 Fox Creek Road Pacific, MO

Yogi Bear's Jellystone Park Resort-Eureka, is a camp resort/entertainment facility. We have guest cottage and cabin rentals, full hook-up rv sites, and tent camping sites. Our guests love visits with Yogi Bear, train rides, themed games, taking a dip in our pool or dunk tank, and being thrilled by our awesome hired...
See info
Elaine Rosi Academy for Children - Wildwood's Photo

Elaine Rosi Academy for Children - Wildwood

1725 Highway 109 Wildwood, MO

1.0(1)
Developmental (play-based)
Child care
Preschool
Elaine Rosi Academy for Children in Glencoe is an early education provider offering infant, toddler, and preschool programs. The company’s curriculum focuses mainly on physical, cognitive, language, and social development. Extra-curricular activities like art and music are also included in each program to ensure that they...
See info
Kids R Kids's Photo

Kids R Kids

123 Hutchings Farm Dr O Fallon, MO

Child care
As a nationally owned franchise headquartered in Duluth, Georgia, Kids R Kids the preschool for toddlers in O'Fallon believes children can be very successful in their early elementary education as a result of the nurturing and learning environment we provide while in our center. We offer an open door policy to our parents in...
See info
VIP KIDS DAYCARE AND RECREATION DEPOT's Photo

VIP KIDS DAYCARE AND RECREATION DEPOT

1306 FEISE RD DARDENNE PR, MO

5.0(1)

State license verified

VIP KIDS DAYCARE AND RECREATION DEPOT is a Child Care Center Located in ST CHARLES County, DARDENNE PRAIRIE City. Best Child Care Center in DARDENNE PRAIRIE MO, Total Capacity of 45 seats and they are accepting Minimum 3 MONTHS to 12 YEARS Kids for Care Services.

Courtney K. says "We were an original family when VIP Kids opened in 2014. We absolutely love it and my daughter has been going since she was ~6 months old. The staff is...

See info

ABC Daycare & Learning Center III

2796 Highway K O Fallon, MO

5.0(1)
Child care
Preschool
ABC Daycare & Learning Center III located in O Fallon, MO is a childcare and a center that serves children from Infant, Toddler, and PreSchool by providing safe, enjoyable, and affordable child care. Their curriculum aims to provide a variety of activities such as Numbers, Math, Science, Colors, and Numbers.

Jamie S. says "My daughter absolutely loves going here. We have gone through a few care cares because of her adhd, so I've had a lot of experiences. They have a low staff...

See info
KIDDIE ACADEMY OF O'FALLON's Photo

KIDDIE ACADEMY OF O'FALLON

4088 WINGHAVEN BLVD O FALLON, MO

5.0(3)

State license verified

Developmental (play-based)
Academic
Child care
Preschool
Educationally-based early childhood learning for children from six week through jr. kindergarten. Our Kiddie Academy proprietary curriculum provides teachers with play-based activities that fill the children's days focusing on the four pillars of our LIfe Essentials Program: (1) developmentally appropriate curriculum, (2)...

Brandon K. says "We've been members of the Kiddie Academy family for six and a half years, ever since our oldest kid was 3 months old. When we started looking for...

See info

Scribbles and Giggles Learning Center

1168 Highway Oo Pacific, MO

3.0(1)
Child care

Steve P says "It closed in 2012. This is a private phone number"

See info
Little Sunshine's Playhouse and Preschool of O'Fallon's Photo

Little Sunshine's Playhouse and Preschool of O'Fallon

4220 STATE RTE N OFALLON, MO

5.0(1)

State license verified

At Little Sunshine’s Playhouse & Preschool, we offer a safe, secure & nurturing environment through our Distinctive Services and proprietary, Reggio Emilia inspired curriculum. We maintain a reputation of unrivaled distinction in preschool and early childhood education making us a sought after, premier private preschool program....

Alexis M. says "We are one of the founding families and have been with LSP since October 2016. All three of my children have gone there, two since birth. They are...

See info

Showing 1 - 20 of 40

How it works

  • Share details about your daycare needs

  • Match with highly rated local daycares near you

  • Compare daycares and tour the ones that best fit your family

Daycare FAQs for Defiance, MO Families

With 0 daycare providers in Defiance, MO, families have real choices when it comes to finding care that fits their child and schedule. Enrolling your child in daycare offers meaningful benefits for both kids and parents. For children, daycare provides structured social interaction with peers, helping them build communication skills, emotional resilience, and confidence from an early age. Daily routines around meals, play, and learning activities support cognitive and physical development in ways that are hard to replicate at home. For parents, a trusted daycare in Defiance provides peace of mind knowing your child is in a safe, supervised environment while you focus on work or other responsibilities. Many families also find that daycare eases the transition to kindergarten by giving children early exposure to a classroom-style setting. If you have an infant or toddler, explore infant daycare options to find programs specifically designed for younger children.

Daycare centers in Defiance, MO offer far more than basic supervision. Most provide structured daily schedules that include age-appropriate learning activities, creative play, outdoor time, and meals or snacks that meet nutritional guidelines. Many centers employ trained early childhood educators who incorporate language development, early literacy, and social-emotional learning into everyday routines. Depending on your needs, you may also find specialized options in Defiance such as infant daycare for babies and young toddlers, family daycare run from a home setting, or overnight daycare for families who need extended care coverage. When comparing providers, look for centers that communicate regularly with parents through daily reports or apps so you always know how your child's day is going.

With 0 daycare options in Defiance, MO, knowing what to prioritize makes narrowing down your choices much easier. Begin by confirming that any center you consider is licensed and in good standing with MO childcare regulations — this ensures minimum health, safety, and staffing standards are being met. From there, pay attention to staff-to-child ratios, staff turnover, and whether caregivers have training in early childhood education or child development. The physical environment matters too — look for clean, organized spaces with age-appropriate materials and secure entry and exit procedures. Don't overlook the daily curriculum: quality centers in Defiance balance structured learning with free play rather than leaning too heavily on one or the other. Reading parent reviews on Care.com is one of the best ways to get an honest picture of what day-to-day life looks like at a center before you visit. Once you've narrowed down your options, our guide on questions to ask when touring a daycare can help you make the most of each visit.

Touring a daycare in Defiance, MO in person is one of the most important steps in the decision-making process, and going in with the right questions makes a big difference. Start with the basics: What are the staff-to-child ratios for your child's age group, and how is the center staffed during drop-off and pick-up? Ask how staff handle discipline and conflict between children, and what a typical daily schedule looks like. It's also worth asking about their communication style — do they use an app, daily sheets, or in-person check-ins to keep parents informed? On the practical side, ask about enrollment availability, waitlist timelines, tuition payment schedules, and their policy on sick days or closures. If you're considering a specific type of care, like a child care center versus a family daycare home, tailor your questions to that setting. For a full list of what to cover, check out our guide on questions to ask when touring a daycare center.

Daycare costs in Defiance, MO vary depending on a number of factors, so it's difficult to give a single number that applies to every family. The type of care plays a big role — child care centers typically have different pricing structures than family daycare homes, which tend to be smaller and sometimes more affordable. Your child's age matters too, as infant care generally costs more due to the higher staff ratios required for younger children. The number of days per week, full-time versus part-time enrollment, and any additional services like meals, enrichment programs, or overnight care will all affect your monthly total. Location within MO is another factor — urban centers in Defiance often see higher rates than suburban or rural providers. For a deeper breakdown of what drives daycare pricing and how to budget effectively, read our guide on the cost of daycare.

Families in Defiance, MO can browse 0 daycare providers across a range of care types, making it easier to find the right fit for your child's age, your schedule, and your budget. Child care centers are larger, licensed facilities that typically serve multiple age groups and offer structured curricula — a good option for parents who value consistency and socialization. Family daycare homes operate out of a caregiver's residence with smaller group sizes, which can feel more nurturing and home-like for younger children. For parents of babies and young toddlers, infant daycare programs are specifically designed to meet the developmental needs of children under two. If your work schedule extends beyond standard hours, overnight daycare may be worth exploring for flexible or non-traditional coverage. Not sure if daycare is the right path at all? Our breakdown of nanny vs. daycare pros, cons, and cost can help you weigh your options.

Daycare Articles

Additional Daycare Services

  • Daycare in Pacific, MO
  • Daycare in Chesterfield, MO
  • Daycare in Gray Summit, MO
  • Daycare in Foristell, MO
  • Daycare in Lake Saint Louis, MO
  • Daycare in Wentzville, MO
  • Daycare in Cottleville, MO
  • Daycare in Eureka, MO
  • Daycare in O Fallon, MO
  • Daycare in Marthasville, MO
  • Daycare in Villa Ridge, MO
About Care.com
  • About us
  • Careers
  • Terms of use
  • Privacy policy
Care.com does not employ any caregiver and is not responsible for the conduct of any user of our site. All information in member profiles, job posts, applications, and messages is created by users of our site and not generated or verified by Care.com. You need to do your own diligence to ensure the job or caregiver you choose is appropriate for your needs and complies with applicable laws.
Care.com® HomePay℠ is a service provided by Breedlove and Associates, LLC, a Care.com company.
Care.com is a registered service mark of Care.com, Inc. 2007-2026 Care.com, Inc. All rights reserved.